can i ask you why are you sure that we will have a cure within 2020? I am also from India. The manufacturer of Propecia (Merck) applied for a patent for topical finasteride in 2002. I reduced dosage again to .5mg every 2 days, same thing happened, sides came back. I would seek medical care if I were you, but try to stay calm. I would pay any amount of money to fix this problem. Both scalp and plasma DHT levels decreased significantly. I know someone recently posted a comment of topical Fin being available via a Spanish company. Sadly big pharmaceutical companies usually put profit margins and stock ratings before clinical efficacy, especially in a field such as dermatology/hairless where mortality is not an issue. Updated on February 22, 2020. Hi Raj I just began using Morrf 5 a week ago. Hey blahblahblah. If you use the other method and pour the compound off the residue on the bottom, you may leave a small percentage of finasteride in the residue. You simply cannot put a price on peace of mind. Thread starter Finssterideruinedme; Start date Feb 27, 2020; Tags finasteride pfs post fin Prev. I know there’s so much available on the forums but they are toxic places I hate visiting and I know there’s a good representation of full heads just starting to bald, right through to completely bald men that follow this blog and I think it would give a good perspective for people considering finasteride. Hi admin, is using topical finasteride harmful to a pregnant lady and child when the husband is using it during this period and the wife comes in contact with the applied solution. The anxiety will be “Is this fin crap even working?” The brain fog will be “What was I doing? These contrast with benign tumors, which do not spread. Would they put out an announcement when they do? How do I deal with it? more effective than topical 17α-estradiol, dutasteride’s superior results to finasteride, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458936/, https://pubmed.ncbi.nlm.nih.gov/26636418/, Yokohama to Begin Hair Multiplication Trials in 2023. I dont want systemic sides if I can lessen them by going topical instead. I diffused a lot those 6 months before getting on propecia. Effects of finasteride on ischemic neuronal damage and the P4-induced neuroprotection in the striatum and cerebral cortex in aged male rats. Been on minox foam for 6 years slowly losing ground. The available studies cited on this site suggest that minox plus finasteride works better. Soothe your symptoms with these fast-relief hayfever treatments, Hay fever symptoms, how can it be treated – and how to tell it apart from Covid-19, With hay fever levels soaring, many may be experiencing various symptoms and wondering if they could be allergic to pollen. You might want to ask your question on one of the hair loss forums out there such as bald truth forums or hair loss talk forums. Some points about finasteride include the following: It takes about four months for any effect to be noticed and up to 1-2 years for full hair growth. I originally wrote this post on topical finasteride in June 2014. If you are diffuse you probably have a lot of hair left in nw3 zone. The study was funded by Swiss company Polichem, which primarily specializes in dermatological and gynecological products. His staff mixes it there. After reading this article, i will purchase Topical Fin from Genhair. Do you recommend it ? Its findings were presented last year at the 7th World Congress on Hair Research (WCHR 2013). Hair Loss. I think serum is the more common one. From what I’ve read, it seems that duta might be more effective on the scalp but so far I’m happy with my program. I probably said March, but apologies if I said February :-). In later stages, symptoms include pain or difficulty urinating, … Did you mean 1mg fin or 0.1 mg? Interesting blog . Many users suffering from long-term sexual side effects have filed a class-action lawsuit against Merck. There was a time I used in daily, but now I stick to 3-4 times a week. How do you think, is it has the same side effect of finasteride? I can’t substantiate that other than my own experience (Fin worked for me the same even as I reduced the dosage). Had some more mild side effects with 1mg topically a day, now doing 0.5-0.6mg/ml with no real effects. Some companies would of thrown in the towel because it’s a money pit or they simply could not succeed. Update: I got an e-mail from the Hasson & Wong clinic on June 17, 2014 stating the following: “Dr. and I’ve noticed worse effects on my skin. Thats what i was thinking to. See your doctor if you have any of the signs or symptoms of moyamoya disease, as early detection and treatment can help prevent a stroke and serious complications. I’m young and my hair is aggressively thinning deffusely; it’s disappearing very fast including noticeably on the sides. I’ve been using it for the past 2 months and I can see definet improvements. A lot of people talking about shaving their head, it’s quite interesting. Also on fin for 18 years. I tried topical Fin from Farmacia Parati in Italy. Note that a similar trial (although at just one dosage level of 0.25 mg per day) for P-3074 was conducted in the past. Would you mind to share your current regimen? I’ll keep dropping by this blog every two weeks until the right solution for me exists! What kind of side effects on skin? Nerve Damage; Scleroderma (hardening of the skin) Liver Cirrhosis; Obstructive Pulmonary Disease ; Kidney Failure; High Cholesterol; Guillain Barre Syndrome; Sickle Cell Anemia; Pelvic Floor Injury; Hypogonadism; Hemachromatosis (too much iron) Periodontitis (gum disease) Enlarged Prostate ; Lack of Vitamin D; Hair loss Drugs (finasteride) Now here’s Jason with … I don’t understand why this is something to celebrate really? I guess Cole didn’t follow up to up inform you of his results. 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P-3074 is a new topical finasteride solution with hydroxypropyl-chitosan as the film-forming agent. Hii raj, im from india too. Getting harder to style but still can hide the balding. With so many different brands to choose from, these are the five best CBD gummies in the UK, 'We are failing our children by not prioritising their mental health enough', We grappled with deaths in the aged but somehow we failed our children by not giving them a high enough priority and now they’re showing serious signs of our neglect, writes Dr Miriam Stoppard, 10 best blood pressure monitors to use at home in 2021, Having issues checking your blood pressure? Recently though read a couple other blogs and started crushing the finasteride and dissolving it into a 5% minoxidil solution (1mg per 1mL initially). Does anyone know a reliable online source to order avodart/dutasteride? Similar to what you did with dutasteride? Hi Jina, May i ask you what effects on the skin you noticed? I also apply a topical retinoid (differin) once a day. Clinical trials in those countries will also be less strictly regulated in my opinion. Each eyebrow gets its own miracle grow. Topical Finasteride. Admin..or anyone else who knows..I note you talk about the ability of topical fin to lower scalp DHT significantly but keep plasma levels the same… 1) I’m a bit confused about the difference between plasma and serum here…any chance you can explain? If you have bothersome side effects, supplement with anastrazole. A new liposomal formulation of topical finasteride is currently available to our European patients. Save my name, email, and website in this browser for the next time I comment. Admin, I’ve followed this forum silently since 2015 and really appreciate your work. I think its due to a certain combination of different things. However, the company has to date never tried to develop an actual product. In people with weak or compromised immune systems — such as people with HIV — both HSV-1 and HSV-2 can cause lasting damage to the eyes and brain. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. I just wondered if there is any evidence that applying it directly to the hair follicles via a spray might have better results? I use simple Minox 5% by alkem pharma and ashwagandha too. P4 markedly reduced neuronal damage 72 h after MCAO, and the P4-induced neuroprotection was apparently suppressed by finasteride in the aged animals. My last hope is oral finasteride, if the hair fall will not be stopped there is no reason for more transplants…. First national phase approval is expected in 2020 or early 2021. How much of fin will enter body per dosage as I know 1 mg oral fin is the max recommended..Thanks.. I’m not saying I want a thick, dense head of hair when I’m 82 (if I live to that age), but I’m almost 39, and hairloss still consumes me. Top Conditions. My second question is how much info do we have on the long term use of finasteride causing brain damage due to deprivation of neurosteroids that are produced by 5AR? It says in the instructions booklet that it is equivalent to applying 50 mg minox and 1mg fin for 1 ml of the product. I’ll give them a dollar per new hair it grows. I have had very little hairloss during this time but have had sexual side effects for sure. Subscribe to Daily Mirror and Sunday Mirror newspapers, 'It's important to discuss and get to the bottom of painful taboo toilet troubles', Miriam Stoppard says it's important to work out what's causing upsets to your digestive system leaving some people with chronic diarrhoea and other debilitating stomach issues, CBD gummies are the most successful product in the rising wave of nationwide CBD use. Again, that might sound ridiculous to some people, but that’s the way I feel. Steroids are commonly used for a wide variety of conditions including asthma, allergies, skin conditions, arthritis and other rheumatological conditions, post-surgical, brain tumors, traumatic brain injury, optic neuritis, giant cell arteritis, lupus, adrenal insufficiency, and more. I’m thinking about shaving my head, how have others handled this initial shock to people? 1. Topical spironolactone:. 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I’ll be one of those guys that shows up one day suddenly with no hair leaving people around him wonder what happened. Science has proven that damage due to Alzheimer’s and other dementias usually starts 10-20 years before symptoms are apparent…symptoms really reflect the brain no longer being able to compensate for the existing and advancing damage to brain cells. I might not have noticed this except I started to use a Q-tip to apply a bit to an area of my eyebrow which is balding. This is the main reason that I am excited about Polichem/Alimrell’s proven product:-) Hope we can get it in the US via import from the EU when it is released. It’s reasonably priced and I know they have been at it a while, yet I don’t see this product mentioned very often. Have not looked at the subject for a long time, so hope that someone else with a scientific background can add to the discussion. Ex through direct contact of husband’s scalp etc. I would consider myself a non responder to Minox but I have been using it for years to try and maintain. Admin, you promised me an exosome update in Febuary. Unless only Hasson and Wong are the only ones distributing it….. ? By doing this, finasteride causes DHT levels in your body to decrease, allowing your hair to avoid DHT-related damage. Just as worrisome as the possible effects in body tissue is the growing evidence that finasteride can enter a man's brain and disrupt key chemicals therein. Thanks. There are probably a couple of reasons for this: 1) I live in an extremely dry climate 2) Differin is an exfoliant and it seems to cast sebum off the scalp leaving it feeling less oily. Try avodart since you tried almost everything else. How is a rat model valid in the case of brain damage caused by finasteride if in rats finasteride inhibits both 5AR-I and 5AR-II, while in humans it does not inhibit 5AR-II which is the main type of AR found in the brain? “Serum DHT was reduced by only -24/-26% with 100 and 200 μL P-3074 and by -44/-48% with 300 and 400 μL P-3074. Those results suck. But I am scared of permanent sides some people are facing. My relationship with friends it’s falling apart because of my attitude…. Before asking any questions, Read the wiki on Finasteride. Not sure what the big deal is with an archaic antiandrogen being developed as a topical. I just wanted to show that you are not alone in the way you feel. Occasionally, yes I do get a couple of hairs that get caught in the roller so I’ve learned to be careful. I have no way of knowing if the growth is the result of the Minox or the finasteride or the adapalene or the result of all three in concert. A bogatyr weighing more than four kilos, and on the Apgar scale only 2 points. If anyone based in the UK wants to get hold of topical Finasteride feel free to contact me as I know a GP that will issue the prescription for a charge following which we have to contact the Italian company to order the product. They will have done their long-term research-sale investment calculations and are probably milking the market for oral finasteride for a given time before bringing out the topical version…, Hi admin any idea when topical dutestride will be commercially available, Hi Dr Robert any idea when topical dutestride becomes commercially available. However, at the time I dealt with it because I knew acne wasn’t forever. You regimen is good. So all you young guys hop on 1mg propecia or else say bye bye to your hair. Once we have secured a reliable source for Dutasteride we will start testing topical formulations with this drug as it will likely be more effective. Tha main issue is not a potential sexual side effect but rather a possible damage to male fetus. I would def use the acne version of breezula when that comes later this year. the regimen you have described is too weak, no wonder you’re falling hard and fast. a P3074 special fan :-). Mine aged fast! Looks like a used car sales man trying to sell you an extended warranty. This preparation can be obtained from this company . At the same time, hair growth benefits will be similar for oral versus topical. Will this substantially reduce the efficacy? where shall we follow latest updates . Has anyone tired this finasteride gel from Strut? Finasteride and dutasteride are frequently prescribed for long-term treatment of lower urinary tract symptoms in men with BPH and in men with AGA. If I ever find a way to cope, I’ll let you know! I used topical finasteride from recommended pharmacy from Belgium . So is there anyway someone in th US can get the topical finasteride? Are you getting thick regrowth or few terminal hairs. Not sure if I can find a physician that would be willing to write a rX for it. Thanks to admin for running this site, I’ve learned a lot. It’s non life threatening and cosmetic. (Source: Gazzetta Ufficiale), Earlier reports noted that ALM12845 no longer fits Almirall’s strategic portfolio and that it was looking for a partner for out-licensing the product.
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